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CBD Oil and Depression

Hemp-derived cannabidiol (CBD) may be a viable alternative to expensive antidepressant medications for the treatment of many forms of depression.

With antidepressants being the third most common psychiatric drug prescribed, the World Health Organization predicts that unipolar depression “will be the second most prevalent cause of illness-induced disability by the year 2020.”  Murray CGL, Lopez AD. Alternative projections of mortality and disability by cause 1990-2020: Global Burden of Disease Study. Lancet 1997;349:1498-504. [PubMed

By definition, depression is a condition of general emotional dejection and withdrawal with sadness greater and more prolonged than that warranted by any objective reason. Between 2009 and 2012, 7.6% of Americans aged 12 and over had depression, with women aged 40-59 having the highest rates.

Studies show that CBD interacts significantly with the 5-HT1A neuroreceptor. This receptor typically binds to and reuptakes serotonin in the brain's neurons, which reduces the amount of free serotonin in the extracellular space. Serotonin is a neurotransmitter known to be key in the treatment of depression; thus, any compounds, such as selective serotonin reuptake inhibitors (SSRIs) or cannabidiol, that increase levels of serotonin, are considered ideal in the treatment of depression.

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CBD Oil and Depression Medical Research

-Antidepressant-like and Anxiolytic-like Effects of Cannabidiol: A Chemical Compound of Cannabis Sativa

-The Endocannabinoid System and the Treatment of Mood and Anxiety Disorders

-Endocannabinoid System Dysfunction in Mood and Related Disorders

CBD Oil and Depression News

-CBD relieves Depression faster than any other Anti-Depressant

-Cannabis as a treatment for Depression

-Home Remedies for Depression